P155Q (p.Pro155Gln) variant of COMP (P49747)
P155Q (p.Pro155Gln) in COMP (P49747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data and structural context.
P155Q (p.Pro155Gln) variant details
- p.Pro155Gln
- ExAC rs749746495
- TOPMed rs749746495
- gnomAD rs749746495
- Missense
- Variant Prioritization Score for Impact Estimate 0.788
- REVEL 0.75
- ESM-1b 1.00
- AlphaMissense 0.64
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.8e-06)
- Structural context available