A153S (p.Ala153Ser) variant of COMP (P49747)
A153S (p.Ala153Ser) in COMP (P49747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
A153S (p.Ala153Ser) variant details
- p.Ala153Ser
- ExAC rs769066350
- gnomAD rs769066350
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.01
- ESM-1b 0.99
- AlphaMissense 0.07
- CADD 21.00
- PolyPhen-2 0.04
- SIFT 0.18
- Most common in the Finnish in Finland (FIN) population (allele frequency 6.1e-05)
- Structural context available