G464E (p.Gly464Glu) variant of COL4A3 (Collagen alpha-3(IV) chain)

G464E (p.Gly464Glu) in COL4A3 (Collagen alpha-3(IV) chain) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as likely pathogenic in the context of Autosomal dominant Alport syndrome; Autosomal recessive Alport syndrome; Benign. The record also includes published literature and structural context.

G464E (p.Gly464Glu) variant details