G340S (p.Gly340Ser) variant of COL1A2 (Collagen alpha-2(I) chain)

G340S (p.Gly340Ser) in COL1A2 (Collagen alpha-2(I) chain) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as likely pathogenic in the context of Combined osteogenesis imperfecta and Ehlers-Danlos syndrome 2. The record also includes structural context.

G340S (p.Gly340Ser) variant details