Y41C (p.Tyr41Cys) variant of CLU (Clusterin)
Y41C (p.Tyr41Cys) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
Y41C (p.Tyr41Cys) variant details
- p.Tyr41Cys
- gnomAD rs1390112562
- Missense
- Variant Prioritization Score for Impact Estimate 0.535
- REVEL 0.54
- CADD 24.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available