Y125S (p.Tyr125Ser) variant of CLU (Clusterin)
Y125S (p.Tyr125Ser) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
Y125S (p.Tyr125Ser) variant details
- p.Tyr125Ser
- Ensembl rs1800822870
- Missense
- Variant Prioritization Score for Impact Estimate 0.61
- REVEL 0.69
- CADD 27.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available