W15R (p.Trp15Arg) variant of CLU (Clusterin)
W15R (p.Trp15Arg) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
W15R (p.Trp15Arg) variant details
- p.Trp15Arg
- 1000Genomes rs180798973
- ExAC rs180798973
- TOPMed rs180798973
- gnomAD rs180798973
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.20
- CADD 22.50
- PolyPhen-2 0.37
- SIFT 0.03
- Most common in the HGDP:NORTHERNHAN population (allele frequency 0.05)
- Structural context available