V9L (p.Val9Leu) variant of CLU (Clusterin)
V9L (p.Val9Leu) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
V9L (p.Val9Leu) variant details
- p.Val9Leu
- gnomAD rs1443898354
- Missense
- Variant Prioritization Score for Impact Estimate 0.32
- REVEL 0.06
- CADD 14.90
- PolyPhen-2 0.04
- SIFT 0.23
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available