V50A (p.Val50Ala) variant of CLU (Clusterin)
V50A (p.Val50Ala) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
V50A (p.Val50Ala) variant details
- p.Val50Ala
- TOPMed rs113632015
- gnomAD rs113632015
- Missense
- Variant Prioritization Score for Impact Estimate 0.414
- REVEL 0.27
- CADD 24.20
- PolyPhen-2 0.34
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available