V101M (p.Val101Met) variant of CLU (Clusterin)
V101M (p.Val101Met) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
V101M (p.Val101Met) variant details
- p.Val101Met
- ExAC rs769302852
- TOPMed rs769302852
- gnomAD rs769302852
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.30
- CADD 23.30
- PolyPhen-2 0.99
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available