T63K (p.Thr63Lys) variant of CLU (Clusterin)
T63K (p.Thr63Lys) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
T63K (p.Thr63Lys) variant details
- p.Thr63Lys
- cosmic curated COSV57067
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.22
- CADD 23.30
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available