T4A (p.Thr4Ala) variant of CLU (Clusterin)
T4A (p.Thr4Ala) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
T4A (p.Thr4Ala) variant details
- p.Thr4Ala
- TOPMed rs1190119879
- gnomAD rs1190119879
- Missense
- Variant Prioritization Score for Impact Estimate 0.131
- REVEL 0.04
- CADD 18.20
- PolyPhen-2 0.00
- SIFT 0.05
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available