T25M (p.Thr25Met) variant of CLU (Clusterin)
T25M (p.Thr25Met) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data and structural context.
T25M (p.Thr25Met) variant details
- p.Thr25Met
- 1000Genomes rs543157739
- ExAC rs543157739
- TOPMed rs543157739
- gnomAD rs543157739
- Missense
- Variant Prioritization Score for Impact Estimate 0.0407
- REVEL 0.01
- CADD 3.86
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the 1KG:PJL population (allele frequency 0.0052)
- Structural context available