T25K (p.Thr25Lys) variant of CLU (Clusterin)
T25K (p.Thr25Lys) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
T25K (p.Thr25Lys) variant details
- p.Thr25Lys
- 1000Genomes rs543157739
- ExAC rs543157739
- TOPMed rs543157739
- gnomAD rs543157739
- Missense
- Variant Prioritization Score for Impact Estimate 0.0461
- REVEL 0.02
- CADD 0.31
- PolyPhen-2 0.02
- SIFT 0.92
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available