S161F (p.Ser161Phe) variant of CLU (Clusterin)
S161F (p.Ser161Phe) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
S161F (p.Ser161Phe) variant details
- p.Ser161Phe
- ExAC rs775465384
- gnomAD rs775465384
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- REVEL 0.12
- CADD 25.40
- PolyPhen-2 0.46
- SIFT 0.00
- Population evidence available
- Structural context available