R158C (p.Arg158Cys) variant of CLU (Clusterin)
R158C (p.Arg158Cys) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
R158C (p.Arg158Cys) variant details
- p.Arg158Cys
- cosmic curated COSV57066
- Missense
- Variant Prioritization Score for Impact Estimate 0.526
- REVEL 0.34
- CADD 27.50
- PolyPhen-2 0.88
- SIFT 0.00
- Population evidence available
- Structural context available