R138S (p.Arg138Ser) variant of CLU (Clusterin)
R138S (p.Arg138Ser) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
R138S (p.Arg138Ser) variant details
- p.Arg138Ser
- ExAC rs757239189
- TOPMed rs757239189
- gnomAD rs757239189
- Missense
- Variant Prioritization Score for Impact Estimate 0.335
- REVEL 0.17
- CADD 26.80
- PolyPhen-2 0.51
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available