P99T (p.Pro99Thr) variant of CLU (Clusterin)
P99T (p.Pro99Thr) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
P99T (p.Pro99Thr) variant details
- p.Pro99Thr
- ExAC rs772883860
- gnomAD rs772883860
- Missense
- Variant Prioritization Score for Impact Estimate 0.18
- REVEL 0.09
- CADD 14.40
- PolyPhen-2 0.27
- SIFT 0.23
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available