N64S (p.Asn64Ser) variant of CLU (Clusterin)
N64S (p.Asn64Ser) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
N64S (p.Asn64Ser) variant details
- p.Asn64Ser
- ExAC rs777850013
- gnomAD rs777850013
- Missense
- Variant Prioritization Score for Impact Estimate 0.221
- REVEL 0.06
- CADD 13.10
- PolyPhen-2 0.09
- SIFT 0.87
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available