N165K (p.Asn165Lys) variant of CLU (Clusterin)
N165K (p.Asn165Lys) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
N165K (p.Asn165Lys) variant details
- p.Asn165Lys
- ExAC rs767422699
- TOPMed rs767422699
- gnomAD rs767422699
- Missense
- Variant Prioritization Score for Impact Estimate 0.0565
- REVEL 0.05
- CADD 0.70
- PolyPhen-2 0.07
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available