M154V (p.Met154Val) variant of CLU (Clusterin)
M154V (p.Met154Val) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
M154V (p.Met154Val) variant details
- p.Met154Val
- ExAC rs765476640
- TOPMed rs765476640
- gnomAD rs765476640
- Missense
- Variant Prioritization Score for Impact Estimate 0.183
- REVEL 0.05
- CADD 16.70
- PolyPhen-2 0.00
- SIFT 0.69
- Most common in the HGDP:PATHAN population (allele frequency 0.021)
- Structural context available