M154T (p.Met154Thr) variant of CLU (Clusterin)
M154T (p.Met154Thr) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
M154T (p.Met154Thr) variant details
- p.Met154Thr
- gnomAD rs1474312346
- Missense
- Variant Prioritization Score for Impact Estimate 0.21
- REVEL 0.12
- CADD 22.20
- PolyPhen-2 0.09
- SIFT 0.04
- Most common in the South Asian population (allele frequency 0.00016)
- Structural context available