M122V (p.Met122Val) variant of CLU (Clusterin)
M122V (p.Met122Val) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
M122V (p.Met122Val) variant details
- p.Met122Val
- ExAC rs751945159
- TOPMed rs751945159
- gnomAD rs751945159
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.08
- CADD 16.30
- PolyPhen-2 0.01
- SIFT 0.52
- Most common in the Non-Finnish European population (allele frequency 7.3e-05)
- Structural context available