M106V (p.Met106Val) variant of CLU (Clusterin)
M106V (p.Met106Val) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
M106V (p.Met106Val) variant details
- p.Met106Val
- ExAC rs779145648
- gnomAD rs779145648
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- REVEL 0.23
- CADD 20.50
- PolyPhen-2 0.40
- SIFT 0.10
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available