M106T (p.Met106Thr) variant of CLU (Clusterin)
M106T (p.Met106Thr) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
M106T (p.Met106Thr) variant details
- p.Met106Thr
- ExAC rs773376852
- gnomAD rs773376852
- Missense
- Variant Prioritization Score for Impact Estimate 0.418
- REVEL 0.35
- CADD 23.40
- PolyPhen-2 0.28
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available