L6Q (p.Leu6Gln) variant of CLU (Clusterin)
L6Q (p.Leu6Gln) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
L6Q (p.Leu6Gln) variant details
- p.Leu6Gln
- TOPMed rs989659621
- gnomAD rs989659621
- Missense
- Variant Prioritization Score for Impact Estimate 0.4
- REVEL 0.24
- CADD 26.10
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available