K78R (p.Lys78Arg) variant of CLU (Clusterin)
K78R (p.Lys78Arg) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
K78R (p.Lys78Arg) variant details
- p.Lys78Arg
- ExAC rs777178481
- TOPMed rs777178481
- gnomAD rs777178481
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- REVEL 0.19
- CADD 25.70
- PolyPhen-2 0.98
- SIFT 0.06
- Most common in the East Asian population (allele frequency 0.0001)
- Structural context available