G18R (p.Gly18Arg) variant of CLU (Clusterin)
G18R (p.Gly18Arg) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
G18R (p.Gly18Arg) variant details
- p.Gly18Arg
- TOPMed rs1800904978
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.25
- CADD 22.70
- PolyPhen-2 0.04
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available