F8L (p.Phe8Leu) variant of CLU (Clusterin)
F8L (p.Phe8Leu) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
F8L (p.Phe8Leu) variant details
- p.Phe8Leu
- ExAC rs772400134
- TOPMed rs772400134
- gnomAD rs772400134
- Missense
- Variant Prioritization Score for Impact Estimate 0.112
- REVEL 0.09
- CADD 8.83
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available