F152Y (p.Phe152Tyr) variant of CLU (Clusterin)
F152Y (p.Phe152Tyr) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
F152Y (p.Phe152Tyr) variant details
- p.Phe152Tyr
- ExAC rs758880085
- gnomAD rs758880085
- Missense
- Variant Prioritization Score for Impact Estimate 0.383
- REVEL 0.23
- CADD 24.10
- PolyPhen-2 0.14
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available