E76V (p.Glu76Val) variant of CLU (Clusterin)
E76V (p.Glu76Val) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
E76V (p.Glu76Val) variant details
- p.Glu76Val
- ESP rs372043736
- ExAC rs372043736
- TOPMed rs372043736
- gnomAD rs372043736
- Missense
- Variant Prioritization Score for Impact Estimate 0.273
- REVEL 0.15
- CADD 24.90
- PolyPhen-2 0.03
- SIFT 0.02
- Most common in the Finnish in Finland (FIN) population (allele frequency 5.6e-05)
- Structural context available