E16K (p.Glu16Lys) variant of CLU (Clusterin)
E16K (p.Glu16Lys) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
E16K (p.Glu16Lys) variant details
- p.Glu16Lys
- Ensembl rs1585256674
- Missense
- Variant Prioritization Score for Impact Estimate 0.294
- REVEL 0.14
- CADD 22.00
- PolyPhen-2 0.26
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available