E112D (p.Glu112Asp) variant of CLU (Clusterin)
E112D (p.Glu112Asp) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
E112D (p.Glu112Asp) variant details
- p.Glu112Asp
- ESP rs370131630
- ExAC rs370131630
- TOPMed rs370131630
- gnomAD rs370131630
- Missense
- Variant Prioritization Score for Impact Estimate 0.295
- REVEL 0.28
- CADD 23.10
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available