D23N (p.Asp23Asn) variant of CLU (Clusterin)
D23N (p.Asp23Asn) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
D23N (p.Asp23Asn) variant details
- p.Asp23Asn
- gnomAD rs1800904153
- Missense
- Variant Prioritization Score for Impact Estimate 0.167
- REVEL 0.07
- CADD 16.40
- PolyPhen-2 0.16
- SIFT 0.09
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available