D166N (p.Asp166Asn) variant of CLU (Clusterin)
D166N (p.Asp166Asn) in CLU (Clusterin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
D166N (p.Asp166Asn) variant details
- p.Asp166Asn
- TOPMed rs1008354423
- gnomAD rs1008354423
- Missense
- Variant Prioritization Score for Impact Estimate 0.289
- REVEL 0.11
- CADD 20.50
- PolyPhen-2 0.03
- SIFT 0.09
- Most common in the East Asian population (allele frequency 7.6e-05)
- Structural context available