L8F (p.Leu8Phe) variant of CLDN14 (Claudin-14)
L8F (p.Leu8Phe) in CLDN14 (Claudin-14) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data and structural context.
L8F (p.Leu8Phe) variant details
- p.Leu8Phe
- TOPMed rs1399944739
- Missense
- Variant Prioritization Score for Impact Estimate 0.721
- REVEL 0.77
- CADD 24.40
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available