L27M (p.Leu27Met) variant of CLDN14 (Claudin-14)
L27M (p.Leu27Met) in CLDN14 (Claudin-14) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data, published literature, and structural context.
L27M (p.Leu27Met) variant details
- p.Leu27Met
- gnomAD 21-36461617-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.687
- REVEL 0.64
- CADD 23.90
- PolyPhen-2 0.96
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available