L22S (p.Leu22Ser) variant of CLDN14 (Claudin-14)
L22S (p.Leu22Ser) in CLDN14 (Claudin-14) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
L22S (p.Leu22Ser) variant details
- p.Leu22Ser
- gnomAD 21-36461631-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.597
- REVEL 0.60
- CADD 24.00
- PolyPhen-2 0.24
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available