I66T (p.Ile66Thr) variant of CLDN14 (Claudin-14)
I66T (p.Ile66Thr) in CLDN14 (Claudin-14) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
I66T (p.Ile66Thr) variant details
- p.Ile66Thr
- gnomAD rs2086574212
- Missense
- Variant Prioritization Score for Impact Estimate 0.294
- REVEL 0.19
- CADD 21.40
- PolyPhen-2 0.03
- SIFT 0.32
- Population evidence available
- Structural context available