G20R (p.Gly20Arg) variant of CLDN14 (Claudin-14)
G20R (p.Gly20Arg) in CLDN14 (Claudin-14) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data, published literature, and structural context.
G20R (p.Gly20Arg) variant details
- p.Gly20Arg
- gnomAD 21-36461638-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.852
- REVEL 0.91
- CADD 25.70
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available