T27I (p.Thr27Ile) variant of CLDN10 (Claudin-10)
T27I (p.Thr27Ile) in CLDN10 (Claudin-10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, published literature, and structural context.
T27I (p.Thr27Ile) variant details
- p.Thr27Ile
- gnomAD 13-95552833-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.631
- REVEL 0.62
- MetaLR 0.56
- MetaSVM -0.04
- CADD 22.60
- PolyPhen-2 0.07
- SIFT 0.13
- Population evidence available
- Structural context available
- Literature evidence available