S22F (p.Ser22Phe) variant of CLDN10 (Claudin-10)
S22F (p.Ser22Phe) in CLDN10 (Claudin-10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
S22F (p.Ser22Phe) variant details
- p.Ser22Phe
- gnomAD 13-95552818-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.6
- REVEL 0.55
- MetaLR 0.54
- MetaSVM -0.15
- CADD 22.60
- PolyPhen-2 0.18
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available