M12V (p.Met12Val) variant of CLDN10 (Claudin-10)
M12V (p.Met12Val) in CLDN10 (Claudin-10) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
M12V (p.Met12Val) variant details
- p.Met12Val
- rs1438067157
- NCI-TCGA Cosmic COSV5482
- TOPMed rs1438067157
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.304
- REVEL 0.23
- CADD 7.22
- PolyPhen-2 0.00
- SIFT 1.00
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available