I8T (p.Ile8Thr) variant of CLDN10 (Claudin-10)
I8T (p.Ile8Thr) in CLDN10 (Claudin-10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
I8T (p.Ile8Thr) variant details
- p.Ile8Thr
- TOPMed rs1313268780
- gnomAD rs1313268780
- Missense
- Variant Prioritization Score for Impact Estimate 0.704
- REVEL 0.84
- CADD 29.70
- PolyPhen-2 0.98
- SIFT 0.03
- Population evidence available
- Structural context available