G37S (p.Gly37Ser) variant of CLDN10 (Claudin-10)
G37S (p.Gly37Ser) in CLDN10 (Claudin-10) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
G37S (p.Gly37Ser) variant details
- p.Gly37Ser
- NCI-TCGA Cosmic COSV5482
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.635
- REVEL 0.64
- CADD 23.00
- PolyPhen-2 0.04
- SIFT 0.58
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available