G31S (p.Gly31Ser) variant of CLCNKB (Chloride channel protein ClC-Kb)
G31S (p.Gly31Ser) in CLCNKB (Chloride channel protein ClC-Kb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
G31S (p.Gly31Ser) variant details
- p.Gly31Ser
- gnomAD rs1316084166
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.07
- CADD 11.70
- PolyPhen-2 0.00
- SIFT 0.86
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available