T84S (p.Thr84Ser) variant of CHRNA4 (P43681)
T84S (p.Thr84Ser) in CHRNA4 (P43681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data.
T84S (p.Thr84Ser) variant details
- p.Thr84Ser
- gnomAD rs1341495482
- Missense
- Variant Prioritization Score for Impact Estimate 0.63
- REVEL 0.75
- CADD 25.40
- PolyPhen-2 0.84
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)