S28C (p.Ser28Cys) variant of CHRNA4 (P43681)
S28C (p.Ser28Cys) in CHRNA4 (P43681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data.
S28C (p.Ser28Cys) variant details
- p.Ser28Cys
- ExAC rs768015799
- gnomAD rs768015799
- Missense
- Variant Prioritization Score for Impact Estimate 0.0975
- REVEL 0.07
- CADD 11.10
- PolyPhen-2 0.01
- SIFT 0.10
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)