R10Q (p.Arg10Gln) variant of CHRNA4 (P43681)
R10Q (p.Arg10Gln) in CHRNA4 (P43681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data.
R10Q (p.Arg10Gln) variant details
- p.Arg10Gln
- TOPMed rs1285617924
- gnomAD rs1285617924
- Missense
- Variant Prioritization Score for Impact Estimate 0.116
- REVEL 0.12
- CADD 5.25
- PolyPhen-2 0.00
- SIFT 0.58
- Most common in the African/African-American population (allele frequency 7.3e-05)