N86S (p.Asn86Ser) variant of CHRNA4 (P43681)
N86S (p.Asn86Ser) in CHRNA4 (P43681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data.
N86S (p.Asn86Ser) variant details
- p.Asn86Ser
- TOPMed rs2068719482
- gnomAD rs2068719482
- Missense
- Variant Prioritization Score for Impact Estimate 0.717
- REVEL 0.79
- CADD 25.80
- PolyPhen-2 0.71
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)